Morus Alba Extract for Prevention and Treatment of COVID-19
A well-defined Morus alba extract with characterized antiviral and antibacterial constituents
Background
Mulberry (Morus sp.) is a medicinal plant used in traditional Chinese medicine (TCM). In addition, Morus sp. extract was shown to be active against influenza virus and pneumococci. For this reason, Morus alba was investigated as source for bioactive constituents that can be used in the fight of global corona-virus pandemic.
Technology Overview
The invention relates to a method for producing an enriched and well-defined extract of bioactive prenylated constituents of Morus alba. The quantitative ratio and composition of constituents contained in the extract causes a distinct in vitro inhibition of SARS-CoV2.
The standardized Morus alba extract was optimized towards:
- High anti-acute respiratory infection activity
- User-friendly production
- Composition enriched in bioactive constituents
Further Details
Grienke et al. (2016), Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae. Sci. Rep. 6, 27156.
Julia Langeder et al.(2019), Natural products against acute respiratory infections: Strategies and lessons learned. J. Ethnopharmacol. 248: 112298.
Stage of Development
- In vitro inhibition of viruses and bacteria in cell culture
- Maximum tolerated dose in mice
Benefits
Natural remedies against lung diseases
- Activity against SARS-CoV2
- Activity against influenza, pneumococci and others
- Prevention and treatment of COVID-19
- High consumer acceptance