Background

Prostate Cancer (PCa) is the most common cancer diagnosed in men in the USA. There were 191,930 newly diagnosed cases in 2020, accounting for 21% of all cases.

PCa is often multifocal, having topographically and morphologically distinct tumor foci. Different tumor foci within the same patients have been reported to be genetically distinct. The multifocal and heterogeneous nature of PCa are important contributors to the difficulties associated with diagnosis and treatment.

Technology Overview

Circular RNAs are a family of endogenous RNAs which have become a focus of biological research in recent years. As they are involved in the progression of cell proliferation, apoptosis, metastasis, and therapy resistance in PCa, circular RNAs have been promoted as cancer diagnostic markers and