Background

Abdominal obesity is the most commonly observed component of metabolic syndrome and a major risk factor for type II diabetes and cardiovascular disease. In addition to obesity, an individual’s risk of cardiovascular disease and type II diabetes is strongly correlated to a series of risk factors, collectively referred to as metabolic syndrome, including insulin insensitivity, elevated plasma triglycerides, hypertension and low plasma high-density lipoproteins (HDLs). Reducing obesity and successfully preventing or treating metabolic syndrome medicinally remains a significant challenge.

Technology Overview

A xanthohumol derived compound with potential as a new drug for treating obesity and reducing the risk of cardiovascular disease and type II diabetes. The metabolism of xanthohumol into phytoestrogen is a challenge for the medicinal use of