Background

Bone bacterial infections, also known as osteomyelitis, are often difficult to cure and exhibit high relapse rates. Osteomyelitis presents a significant health burden, with 22 cases per 100,000 individuals in the United States with a recurrence rate of 20-30%.

Technology Overview

Researchers at McMaster University have developed a phage-loaded injectable hydrogel treatment for osteomyelitis infections.The phages are delivered to the site of infection to treat the bacterial infection, while the hydrogel promotes bone tissue regeneration.

Benefits

• Minimally invasive solution for addressing recurring bone and implant infections
• Effective at reducing bacterial infection
• Hydrogel is able to protect phages from external factors