Background

Disturbances of memory and cognitive functions characteristic of patients with Alzheimer’s disease are the result of a severely reduced concentration of the acetylcholine transporter in the brain. Inhibition of acetylcholine hydrolysis in the brain is used to increase acetylcholine concentrations, thereby alleviating memory disorders, restoring cognitive function, and relieving symptoms of Alzheimer’s disease and similar dementias.

Technology Overview

The drug University of Ljubljana researchers developed inhibits the hydrolysis of acetylcholine in the brain, thereby alleviating symptoms in dogs suffering from canine cognitive impairment, dementia similar to Alzheimer’s disease (). The present invention is being tested in dogs with symptoms of AD. The goal is to commercialise the drug for veterinary use and further test it for human use.