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Appetite-Suppressing Cytokinin for Weight Loss and Obesity Treatment
Plant-derived cytokinin that induces weight loss as a supplement or therapeutic
Obesity has increased to pandemic levels and is associated with an increased risk of metabolic diseases, including type 2 diabetes mellitus (T2DM), cardiovascular disease and cancer. While the most effective means to reduce weight is healthy eating and exercise, adherence to these recommendations are a challenge, especially in individuals with a high body weight or BMI >30. Alternatives to these solutions include anti-obesity therapeutics and supplements. Limited therapeutic options are approved by the FDA, such as Glp-1R agonists, but they are restricted to high BMI patients, are costly for insurers/individuals, have limited efficacy or have unpleasant side effects. Similarly, several supplements are available, but none are regarded as being efficacious unless combined with diet and exercise. Consequently, an unmet
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