Technology Overview

Researchers at Berkeley Lab have invented the only noninvasive vasorelaxation assessment technique to achieve the previously unprecedented accuracy of invasive methods that use artificial pulses to obtain pulse wave velocity. The Berkeley Lab method will enable the inexpensive and routine detection and monitoring of preclinical cardiovascular disease (CVD) via endothelial function. It can also be used to assess the efficacy of statins and other regimens for aiding arterial health as well as for detecting occlusion in limbs ().

Comparing the sensitivity of artificial PTT with artery diameter measurements ()

Berkeley Lab studies on human subjects have verified that the new method is 37% more sensitive to arterial relaxation than brachial artery (BA) imaging. In addition, the apparatus costs