You are viewing a preview of...

Novel Antivirals for Enveloped Viruses

Small organic molecules that are able to lyse membrane lipids with potential application against enveloped viruses such as Covid-19

Technology Overview

Durham researchers have identified small organic molecules that are able to lyse membrane lipids. These agent shave potential application against enveloped viruses as a consequence of this lytic activity. If successful, their mode of action would be novel.

The mode of action exploits chemical processes that have been identified at Durham (), whereby some functional groups are reactive towards chemical components of lipid membranes, leading to their chemical transformation within the membrane. This transformation can be detrimental to viability. Membranes with lipid compositions similar to those of enveloped viruses such as Covid-19 are reactive. There is chemical selectivity within this process, both at the level of the molecule (some functional groups are reactive, others are not) and the

Log in or create a free account to continue reading