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Monoclonal Antibodies to Detect SARS-CoV1 & SARS-CoV2

Monoclonal antibodies that cross bind to SARS-CoV1 & SARS-CoV2 and can therefore act as diagnostic or detection agents

Technology Overview

COVID-19 is caused by infection with SARS-CoV2.

Two mouse monoclonal antibodies (mAb’s) are presented, one which specifically binds to the Spike protein (S) and the other which specifically binds to the Nucleocapsid protein (NP), both of which recognize SARS-CoV1 & SARS-CoV2, but do not bind to other beta-coronaviruses.

Stage of Development

  • Two mouse monoclonal antibodies that are specific to the Spike protein and Nucleocapsid protein as measured in Western Blot, ELISA and flow cytometry
  • One mouse monoclonal antibody that binds specifically to spike of SARs-CoV1 and neutralizes SARS-CoV1

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